https://www.ceesdekker.net - An Overview
https://www.ceesdekker.net - An Overview
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Applying solitary-molecule optical and AFM imaging and power-spectroscopy methods, we seek to unravel the mechanistic components of the framework and dynamics of chromosomes. Our analysis interests involve:
1996, very first mesoscopic demand density waves devices; and very first electrical measurements on a single metal nanocluster involving nanoelectrodes
Dynamics of initiation, termination and reinitiation of DNA translocation via the motor protein EcoR124I
Sculpting nano-electrodes by using a transmission electron beam for electrical and geometrical characterization of nanoparticles.
De sterke polarisatie in de discussie rond schepping/evolutie en meer algemeen rond geloof/wetenschap lijkt helaas geen eind te kennen. Toch is er wel degelijk een heilzame middenweg, maar deze krijgt more than het algemeen weinig aandacht. Dit boek kan hier wellicht verandering in brengen. Wie de geschiedenis van de relatie tussen geloof en wetenschap in duikt, komt tot verrassende inzichten. De moderne mens leeft met veel stereotypen die historisch niet verantwoord blijken te zijn. Afgezaagde typeringen als ‘Vroeger dachten we dat de
Illustration (3) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim of your pore is highlighted in purple, along with a 3D rendering of the movement from the DNA rod is exhibited.
Since 2000 he moved to one-molecule biophysics and nanobiology, with investigation from DNA supercoiling reports of nucleosomes and DNA fix proteins to DNA translocation through nanopores. Recently his exploration has focused on studying mobile division with germs on chip, while his best curiosity is within the way of knowing synthetic cells.
Case in point (1) of bending configurations in 3D simulations of DNA rods on nanopores. A percentage of the membrane is proven in gray, the rim in the pore is highlighted in pink, as well as a 3D rendering of the movement of the DNA rod is shown.
What if, in place of making use of conventional top rated-down silicon electronics, transistors could possibly be constructed from The underside up utilizing one natural molecules given that the switching factors? This concept, which became The premise of these days’s subject of molecular electronics, initial emerged within the seventies.
There was one particular trouble though — we did not observe any measurable electrical conduction from the single polymer molecules. We concluded that at the single-molecule level, conducting polymers were truly not these kinds of good conductors, which was alternatively disappointing. We thus broadened our see to try to seek out far more promising molecules.
Since 2000 he moved to one-molecule biophysics and nanobiology, with analysis from studies of DNA loop extrusion and supercoiling to DNA translocation by nanopores. Much more a short while ago his investigation has focused on finding out chromatin structure and cell division with bacteria on chip, even though he is additionally attempting to eventually build artificial cells from The underside up.
Nanoscientist Cees Dekker is surely an amiable and flamboyant male who appears Considerably more youthful when compared to the 62 several years he basically is – stylish Eyeglasses, psychedelic shirt, partaking smile – although not 1 to squander time. He will take his time, but not more than essential.
By way of example, we consider the nucleopore elaborate, a gateway concerning the cell nucleus as well as the cytoplasm. This is a really challenging program and thus difficult to review inside of a cell, so we use biomimetics. We reconstruct holes and after that insert individual things on the nucleopore sophisticated to check transport through it at The ceesdekker.net one-molecule degree.’
‘I am pushed by speculate and questions. On a material degree I uncover responses in physics, but I working experience my deepest happiness with God. That faith also drives my science And the way I take care of persons.